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Recent advances have also shown that Cas proteins can be engineered to alter PAM recognition, opening new opportunities to develop CRISPR-based tools with enhanced targeting capabilities.
Therefore, mitigation efforts to offset impacts from sea-level rise and storms can also be engineered to alter, or even reduce, the effects of climatic change on biological assemblages.
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Naturally occurring enzymes have also been engineered to alter their activities and specificities for use in synthetic, environmental and medical applications [7].
Tobacco mosaic virus mutants were engineered to alter either the stability or surface chemistry of the virion: within the coat protein, glutamic acid was exchanged for glutamine in a buried portion to enhance the inter-subunit binding stability (E50Q), or a hexahistidine tract was fused to the surface-exposed carboxy terminus of the coat protein (6xHis).
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The ability to perform quantitative studies using isotope tracers and metabolic flux analysis (MFA) is critical for detecting pathway bottlenecks and elucidating network regulation in biological systems, especially those that have been engineered to alter their native metabolic capacities.
Recent discoveries highlighting the metabolic pliability of plant lignification indicate that lignin can be engineered to dramatically alter its composition.
Recent discoveries highlighting the metabolic malleability of plant lignification indicate that lignin can be engineered to dramatically alter its composition and properties.
These DNA scanners can also be engineered to detect designer pathogens altered to be more deadly.
Antibodies can also be engineered to resist proteolysis by altering the amino acid sequence to eliminate proteolytic sites.
These versatile materials can furthermore be engineered to encompass biomedical applications in addition to providing improved hardness and other such uses in altering the base materials.
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