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Group I ribozymes can be engineered to act in trans by recognizing a separate RNA molecule in a sequence-specific manner, and to covalently link a new RNA sequence to this separate RNA molecule.
Multiple cell types have demonstrated sensitivity toward mechanical and topographical cues in their environment, suggesting that the nanocomposite film morphology may be engineered to act synergistically with electrically controlled drug release to provide additional signals to the targeted cell population.
High stability and accessibility of DNA circles by cellular proteins have led us to suggest that stable circular DNA intermediates can be engineered to act as putative substrates for gene insertion by nonviral gene-inserting proteins.
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Two of the three classes of ribozymes have been engineered to act as true enzymes, catalyzing the multiple-turnover transformation of substrates into products.
Transfer films have been engineered to act as solid lubricants between sliding surfaces in environments where fluids cannot exist or are not desired.
Plant viruses have also been engineered to act as adjuvants to elicit an immune response that is more potent and effective.
In addition to applications in imaging of protein expression level and subcellular localization, fluorescent proteins have been increasingly engineered to act as biosensors to track concentrations of small-molecule metabolites, enzyme activities, and protein conformational changes in living cells.
This ambitious project, which began in 2009 aims to build a swimming robot with cells that have been genetically engineered to act like eyes, cells that detect chemicals, and muscles that contract, says Frankel. "All of these components will eventually work together like an artificial organism".
Furthermore, PEDF was unable to act upon cells that had been engineered to make less of these two receptors.
The "plot" has obviously been engineered to put Joe through every kind of sex act.
Whereas SOX17 has been engineered to replace SOX2 in the pluripotency circuitry, all generated SOX2 mutants have failed to act like SOX17.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com