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In this study, we compared nCounter with microarray expression measurements of an experimental dataset composed of leukocyte subset RNA from healthy controls and patients with either anti-neutrophil-cytoplasmic-antibody-associated vasculitis (AAV) or inflammatory bowel disease (IBD) to exemplify the level of biological variation likely to be encountered in microarray experiments.
Similar(59)
This again is an issue that, in principle, can be encountered in all types of medical studies, but affects microarray studies more drastically.
The described microarray datasets were selected as representatives of the diversity of RNAi investigations that would most likely be encountered in a 'typical' RNAi analysis.
Other situations may be encountered in practice.
We use the microarray datasets to determine whether significant bias is encountered in this gene expression data.
Infection was encountered in one patient.
Minor complications were encountered in two cases.
10 injuries were encountered in 7 patients.
No pseudotumors were encountered in either group.
Complications were encountered in two patients (5.5 %).
Complications were encountered in nine (8.8%) patients.
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