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We propose that this was enabled by the evolution of germ plasm, which transitioned PGC specification from zygotic control to cell-autonomous regulation by inherited cytoplasmic factors.
Interestingly, early germ line determination may have been enabled by the evolution of a novel foetal membrane, the ExE, which expresses high levels of Bmp4.
Online process control is enabled by using the evolution of the peak current densities in the cyclic voltammograms as online-indicator for the growing electrode surface area.
This evolution is enabled by the creation of state-of-the-art software, which has helped make wealth management more consumer-friendly, affordable and accessible than ever before.
This evolution is enabled by recent advances in biotechnology, including cultivation of non-model microbes, metabolic engineering, bioinformatics, and numerical modeling.
Dense methylation is enabled by a regime of genomic sequence evolution that enriches CG dinucleotides and drives the highest CG frequencies known.
This route of evolution conceivably was enabled by the virtual sequestration of intracellular parasites and symbionts from HGT and by the ensuing reduction of the effective population size 61, 62.
Our analyses were enabled by a flexible, simulation-based model of CRM evolution, called PEBCRES (He et al. 2012; Duque et al. 2014).
Environmental induction of novel phenotypes, where phenotypic retention of adaptive developmental variation is enabled by organismal complexity and homeostasis, can be a starting point in the evolution of some adaptations, but empirical examples are rare.
