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Lipocalin-2 has been reported to be elevated in certain metabolic disorders, including obesity, polycystic ovary syndrome and type 2 diabetes [ 11, 13, 17].
TAGs were previously noted to be elevated in certain daf-2 mutants, although not correlated with the lifespans of those alleles [ 9].
While concentrations of TNF-α and IL-1β appeared to be elevated in certain subgroups of patients, the role of confounding factors, such as age and obesity, should be taken into account when planning future research on these immune markers.
A logical approach to target glycolysis is to inhibit LDH, which is an NADH-dependent enzyme that converts pyruvate to lactate and has been shown to be elevated in certain cancer cells [3], [170].
Paradoxically however, TIMP-1 expression has been found to be elevated in certain malignancies, and high levels of TIMP-1 expression in tumours, by either tumour or stromal cells, are predictive of poor patient prognosis with regard both to the length of the disease-free interval and to survival rate (Ree et al, 1997; McCarthy et al, 1999; Nakopoulou et al, 2002).
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ZnPP/H is elevated in certain infant subpopulations, which suggests that they may require additional iron supplementation.
These results indicate that SCCA expression is elevated in certain breast cancers.
Taken together, these results indicate that expression of SCCA is elevated in certain breast cancers and may correlate with invasive ductal carcinoma.
SCCA was detected at various levels in 5 out of 6 of the breast cancer cell lines (Fig. 2A), indicating that SCCA expression is elevated in certain types of breast cancers.
Although the precise function of QSOX1 remains elusive, what is known is that the expression of the enzyme is elevated in certain disease states.
Expression of Pkm2 is ubiquitous in the CNS but is elevated in certain structures such as the ventricular zone that lines the left ventricles and the inferior colliculus of the midbrain.
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