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The paper highlights different situations encountered when a chemical reaction is to be elaborated into a synthetic method.
At an appropriate point in the enzymatic synthesis, the unnatural monosaccharides can be converted into their natural counterpart, allowing each arm to be elaborated into a unique appendage.
In turn, these images were to be elaborated into scenario narratives, reflecting the influence of other events and trends beyond and in addition to those depicted on the two axes.
Ligand efficiency is the free energy of binding divided by the number of heavy atoms [5], [6], and is commonly used to predict if a ligand can potentially be elaborated into a good inhibitor, and to rank hit compounds in order to choose the best lead molecule.
K-turns can be elaborated into more complex forms, including the k-junction.
The fact that binding of glycerol to Gal3C could not be detected in solution at room temperature yet occurs perfectly as a fragment lead that can be elaborated into lactose emphasizes the important role of protein crystallography in fragment-based drug discovery.
Similar(54)
It could begin with something like primitive vocalizations, which gradually become more infant-directed, and are elaborated into melodies.
Quantum theory, first proposed by Max Planck in 1900, has been elaborated into a comprehensive description of the very small.
What began as an unsubstantiated guess about Ingres has merely been elaborated into a highly marketable myth.
But sometimes these folk beliefs, or intuitions, are elaborated into scientifically testable schemes – even empirically testable ones.
In each iteration through the spiral process, a number of use cases are elaborated into an executable, validated prototype.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com