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Furthermore, bioactive BMP-2 could be efficiently released from the carrier-beads.
Furthermore, in vitro cellular uptake study results showed that the entrapped drug could be efficiently released from MSNs-PLH-PEG under acidic endosome/lysosome.
The test shows dichloroacetate can be efficiently released from complex 2 under physiological conditions via the hydrolysis of an ester bond bridging the dichloroacetate moiety and platinum pharmacophores together.
First, miR-146b-3p could be efficiently released from cancer cells into circulation such that it does not accumulate in the tumour.
Although further studies are needed, the EPND release profile suggests that a low concentration of free drug molecule in serum can be expected, since Epirubicin would not be efficiently released from nanodiamond in a pH of 7.4.
Since some ER lumen chaperones are also co-localized with the protein inclusions, our results suggest that misfolded proteins cannot be efficiently released from ER in the absence of SIL1 function in Purkinje cells, resulting in accumulation and aggregation on the ER surface.
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Dox is efficiently released from the hairpin following cell uptake and Dox retains potency as an anticancer drug.
On heating the catalyst in glycerol, CaO is efficiently released from the carbon support into the reaction medium.
Interestingly, Par14 also associated at low salt concentrations with mitochondria, but was efficiently released from mitochondria at physiological or higher salt concentrations (80 mM NaCl corresponded to physiological conditions within this experimental buffer system [ 28]).
Like the Drosophila histones, H1 was efficiently released from the LDs by LPS, consistent with the hypothesis that the accumulated H1 on the hepatic LDs can be released by the presence of cytosolic bacteria, and thus might contribute to an antibacterial response.
For example, any still trapped in capsids might not have been efficiently released by SDS/proteinase K treatment.
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