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We first demonstrate that T cells can be efficiently loaded with 45 nm gold colloid nanoparticles without affecting viability or function (e.g. migration and cytokine production).
Following short term incubation with AuNPs, T cells can be efficiently loaded with over 14,000 AuNPs per cell without affecting cell viability, proliferation, and cytokine production.
The advantages of using a carbon nanotube-assisted drug delivery system include efficient targeting and amplification of tumor targeting due to an enhanced permeability and retention effect of the carbon nanotube which can be efficiently loaded with the drug.
GO-DEN(Gd-DTPA -mAb can be efficiently loaded with doxorubicin hydrochloride (DOX), and the resultinGd-DTPA -mAbDTPA)-mAb/DOX exhibits enhanced cytotoxicity to PC-3 cells due to Gd-DTPA -mAbng performancan
Finally, CB[7] can be efficiently loaded with the anti-tuberculosis drug ethambutol (EMB) and be used for treatment of macrophages infected with mycobacteria.
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We have previously shown that DNA replication origins relocated to the VPS13 locus are efficiently loaded with pre-RC protein complexes ORC and MCM, and can initiate DNA synthesis in S phase [ 11].
For example, curcumin could be efficiently loaded in CCM3 and CCM4 at 10 1 polymer/drug ratio with the homogeneous particle sizes of 14 and 18 nm, respectively, as shown in Supporting Information Figure S17.
Mitoxantrone can be efficiently loaded into large unilamellar vesicles using a transmembrane pH gradient.
Paclitaxel was efficiently loaded in nanomicelles with highest loading efficiency (LE) of 75% which was influenced by the composition of the copolypeptide block.
Results indicate that by impregnation treatment, agar gel was efficiently loaded in porous lightweight aggregates, thus CA with a resistivity of 0.5 Ω·m was obtained.
Rhodamine-123 was efficiently loaded on the PCL-NP approaching 70% of the dye initially added.
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