Cadmium was efficiently accumulated in nature to a mean concentration of 119, 33, and 50 micrograms/g wet tissue in the hepatopancreas of three species of molluscs, and 30%, 11%, and 43% of the element in each tissue of whelk, turbo, and squid was extracted to the soluble fraction, respectively.
The probe is efficiently accumulated into secretory granules in β-cell-derived lines and isolated islets, but more poorly by non-endocrine cells, and leads to a reduction in T1 in human islets.
Methylmercury is efficiently accumulated through estuarine food webs, such that concentrations in fish are controlled by initial CH3Hg+ assimilation at the base of the food web.
A fundamental problem of asexual adaptation is that beneficial substitutions are not efficiently accumulated in large populations: Beneficial mutations often go extinct because they compete with one another in going to fixation.
Furthermore, the arrested cells were more efficiently accumulated in the population of area B than in the population of area C, indicating that signaling through the GJP plays a significant role in bystander cell-cycle effects.
However, acetyl-CoA is not always efficiently accumulated in M. extorquens AM1, as it is located in the center of three cyclic central metabolic pathways.
OxbCD NP was able to efficiently accumulate in the inflamed colon in mice, thereby dramatically reducing nonspecific distribution after oral delivery.
Once absorbed by ingestion or inhalation, Cd efficiently accumulates in the organism, in particular in the kidneys, where it is retained with a biological half-life exceeding 20 years.
Experiments presented in this study indicate that PEG-liposomes efficiently accumulate in tumor tissue, and maintain a high level over 24 h, which is in concordance with previous reports from other groups [ 31, 34].
