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This method using S A thresholds with data-driven assessment methods like LR proves to be efficient when applied to common spatial data and establishes a methodology that will allow similar studies to be undertaken elsewhere.
Although there are several algorithms to detect CNAs in exome sequencing data (Amarasinghe et al., 2013; Boeva et al., 2011; Li et al., 2012), it is questionable as to whether the same approaches can be efficient when applied to amplicon sequencing data.
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Their protocols were based on an algorithm by Wiedemann for "black-box linear algebra" [10] which was efficient when applied to sparse matrices.
BZ194 was efficient when applied before the T cells came in contact with antigen-pulsed antigen presenting cells.
Even if the proposed algorithms have proven to be very efficient when applied to specific synthetic cases, most of them have failed — or have been only partially successful — when dealing with real, complex reservoirs.
Dimension reduction technique is well known as substructuring or superelement creation (for example, see [4]) and turned out to be very efficient when applied to considered type of contact problems.
However, the latter approach would be less efficient when applied to complex traits affected by numerous QTL of varying effects, while genomic selection is well suited to handle this situation.
This method could be more efficient when applied as the last step of the multiple-step polishing systems [26].
The developed estimation algorithm shows to be computationally efficient when applied in the context of large antenna arrays.
In spite of this, proposed algorithm proves to be very efficient when applied to the graphs of the investigated real systems.
Exome sequencing might be most efficient when applied to patients with more extreme forms of common diseases, such as morbid obesity; first, it increases the chances to obtain significant association for rare variants with high penetrance; second, genetic variants in the protein coding sequence might be more likely to have a strong impact on the phenotype than variants in intergenic regions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com