Also, intrathecal administration of 4D5, the murine precursor of trastuzumab, shows efficacy against a human xenograft of Her-2-overexpressing cancer growing in the leptomeninges, suggesting that trastuzumab could be efficacious if it could penetrate the blood-brain barrier [ 26].
If the program proves to be efficacious, a subsequent step could be a comparative effectiveness study with face-to-face treatment [ 61].
We believe the results of the TPOP will be of importance: accidental injury occurs across the globe and omega-3 fatty acid supplementation, if found to be efficacious for preventing PTSD, could maintain the mental health of the injured.
If found to be efficacious, this low-cost intervention could be easily disseminated with significant potential for reducing the risk of negative cancer outcomes associated with continued smoking.
If shown to be efficacious and safe, these devices could help many smokers as an alternative smoking cessation aid to standard nicotine products.
If the intervention is efficacious, this could potentially influence clinical practice and health policy.
If PEPs are efficacious, they could avert not just HIV but other infections that are entrenched in marginalised populations (eg, viral hepatitis), as well as improve the uptake of SEPs and substance use treatment modalities.
On the other hand, it is still unclear whether targeting the branched-chain amino acid biosynthesis in vivo could be efficacious in context of an antifungal chemotherapy (Richie et al. 2013).
These outcomes provide a better understanding of the role of Nrf2 in modulating autophagy in an AD mouse model and may help design better Nrf2 targeted therapeutics that could be efficacious in the treatment of AD.
Still, Nixon can be said to have been the last Republican president who accepted the idea that federal programs could be efficacious.
