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To date, individual cognitive-behaviour therapy (CBT) has been found to be efficacious in three randomized controlled trials (RCTs).
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In order to lower the impact of placebo effect on our results, we considered patients as responders only if OnaA treatment was efficacious in two consecutive sets of injections.
Here we demonstrate that WAY-169916 is efficacious in two models of arthritis, the HLA-B27 transgenic rat and a Lewis rat model of adjuvant-induced arthritis.
There has been increasing evidence that rituximab is effective for the treatment of membranous nephropathy [ 12– 14], and this treatment has been efficacious in six of seven isolated cases of anti-GBM disease (Table 1) [ 15– 15].
Skin-to-skin contact by the mother, referred to as Kangaroo Mother Care (KMC), has been shown to be efficacious in reducing pain in three previous studies.
5 Two prophylactic vaccines against human papillomavirus (a bivalent vaccine against types 16 and 18 and a quadrivalent vaccine that also includes types 6 and 11) have been shown to be efficacious in up to five years of follow-up against types 16 and 18 cervical infection and associated disease as well as against anogenital warts.
Similarly, when each trial was limited to one OMT vs control treatment comparison, OMT was found to be efficacious in each of the four analyses.
Both the "severity" of sentencing and the "certainty" (or lack of it) of getting caught and convicted have an effect on crime and imprisonment rates; one cannot be efficacious in the absence of the other.
While subsequent uncontrolled studies found fluoxetine, fluvoxamine and citalopram to be efficacious in patients with hair pulling [ 106– 110], two controlled studies [ 111, 112] with fluoxetine could not replicate the positive findings reported with SSRIs in the open-label trials.
In Australia, two TCM products were shown to be efficacious in the treatment of irritable bowel syndrome and hepatitis C [ 58, 59].
Ten of the 11 plants that were found to be efficacious in this study demonstrated varying degrees of toxicity to IR HepG2 cells at different concentrations.
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