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Strategies to reverse aberrant gene silencing have been demonstrated to be efficacious in specific cancers, and clinical trials are ongoing to evaluate drugs targeting epigenetic regulation of gene expression [ 32, 33].
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19 AONs were found to be efficacious in inducing specific exon skipping (83% of total), of which 14 were considered efficient (61% of total), i.e. induced exon skipping in >25% of total transcripts.
Uncontrolled observational and histologic studies suggest thymectomy may not be efficacious in anti-muscle-specific kinase (MuSK -MG.
The nine serotypes included in PCV9 covered 83 91% of invasive disease causing serotypes among HIV-infected children prior to the study., PCV was found to be efficacious in preventing vaccine serotype-specific IPD in HIV-infected infants, who were not on ART.
Sublingual specific immunotherapy has been proven to be efficacious in treating type I allergies.
Therefore, although there is limited specific evidence, this treatment is likely to be efficacious in an environment when nearly all patients receive temozolomide as part of initial management.
Despite nearly 30 years of research, no specific pharmacological therapy has yet proven to be efficacious in manipulating the pathophysiological processes that underlie this condition.
Developer-led trials of both have shown them to be efficacious in reducing symptoms of depression.
Cidofovir has been found to be efficacious in treating RRP.
I figured a "blockbuster" drug would be efficacious in more than 50percentt of the people who took it.
This suggests that a recombinant vaccine designed to be efficacious in Africa and Asia is likely to be efficacious in South America.
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CEO of Professional Science Editing for Scientists @ prosciediting.com