Sentence examples for be efficacious in randomized from inspiring English sources

Antidepressants, gabapentin, pregabalin, opioids, and topical lidocaine have been shown to be efficacious in randomized controlled studies [8, 9] and many other drug therapies, interventional approaches, and psychological or rehabilitative treatments are tried empirically in those with persistent pain [10 13].

Fortunately, several preventive interventions for children with family adversity have been developed and found to be efficacious in randomized controlled trials [ 2, 7, 12, 17, 26, 32].

This initiative, Head-off Environmental Asthma in Louisiana (HEAL), sought to reduce asthma morbidity in children with asthma by employing a combination of evidence-based interventions shown to be efficacious in randomized, controlled clinical trials (Evans et al. 1999; Morgan et al. 2004).

To date, individual cognitive-behaviour therapy (CBT) has been found to be efficacious in three randomized controlled trials (RCTs).

The folate antagonist methotrexate has not proven to be efficacious in a randomized trial to treat patients with moderately active steroid-refractory UC.

After radiotherapy was found to be efficacious in a randomized trial, the next therapy shown to improve survival in such trials in this disease was the carmustine implant in patients with recurrent disease in 1995 3 and newly diagnosed patients in 2003. 1, 2 Because of the poor outcome of this disease, there was and continues to be great interest in developing new therapeutic approaches.

She has developed a targeted psychotherapy, Complicated Grief Treatment, for people unable to move forward after a loss, which has proved to be efficacious in three NIMH-funded randomized controlled trials.

To date, drotrecogin alfa (activated) is the only therapy that has been demonstrated to be efficacious in severe sepsis by a large, randomized, double-blind, placebo-controlled trial.

Lamotrigine has been shown in randomized controlled studies to be efficacious in preventing bipolar depression and rapid cycling states.

Prior data suggest that angiotensin converting enzyme inhibitors (ACEi) may be efficacious in enhancing exercise-derived improvements in functional status yet this hypothesis has not been tested in a randomized controlled trial.

Developer-led trials of both have shown them to be efficacious in reducing symptoms of depression.