Sentence examples for be efficacious in only from inspiring English sources

Furthermore, many new targeted therapeutics are likely to be efficacious in only one subgroup, such as smoothened inhibitors for SHH pathway-driven MB [ 1, 2].

Each drug is efficacious in only 60 70% of patients.

Golimumab, one of the newest TNF blockers, was recently shown to be efficacious in improving not only the signs and symptoms of PsA, but also in treating the structural damage caused by the disease making it a reasonable option in treating moderate to severe PsA.

If blood COHb levels indeed reflect the amount of CO delivered to peripheral tissues, it is possible that inhaled CO would only be efficacious in humans once COHb reaches 'close to toxic' levels comparable to those achieved in rodent studies (e.g. 15 30%).

Thus, immunotherapy against disease proteins may only be efficacious in treatment of NDs early during the course of disease.

On the basis of previous research, we assumed that 54% of the population at large would have positive skin test results and that SCIT would only be efficacious in 51% of the population.

This may indicate that the D-enantiomers of the ceramide analogues we have used have additional actions (either direct or indirect) on APP processing that remain to be discovered and that inhibition of GSL synthesis alone (i.e. using siRNA targeting) may only be efficacious in situations where membrane GSL levels are increased above their physiological concentrations.

In 1998 the only drugs available to treat pulmonary hypertension were calcium channel antagonists and intravenous epoprostenol, although epoprostenol was only shown to be efficacious in children with IPAH in 1999.

To date, drotrecogin alfa (activated) is the only therapy that has been demonstrated to be efficacious in severe sepsis by a large, randomized, double-blind, placebo-controlled trial.

Gefitinib and erlotinib, currently used in lung cancer, inhibit only EGFR and have not been shown to be efficacious in HNSCC to date.

I figured a "blockbuster" drug would be efficacious in more than 50percentt of the people who took it.