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A copper chelator known as diacetylbis(N(4 -methylthiosemicarbazonato) copper II (CuATSM), has been reported to be efficacious in multiple transgenic SOD1 models of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder affecting motor neurons.
Therefore, previously described HIV epitopes are biased towards well-studied populations that do not represent the majority of HIV-infected subjects, and studies that compare epitope recognition between populations are important to guide the design of vaccines that aim to be efficacious in multiple populations.
See related editorial by Scott and Kingsley, http://arthritis-research.com/content/12/2/115 Biologic therapy for rheumatoid arthritis (RA) has been shown to be efficacious in multiple clinical trials [ 1- 10].
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Although its development has been discontinued, AMGN-0007, a recombinant OPG construct, was shown in early studies to be efficacious in patients with multiple myeloma or breast cancer related skeletal metastases.
The effects of ATO were subsequently examined in other tumor types, including multiple myeloma, glioma, neuroblastoma, esophageal carcinoma and prostate cancer, and it has been found to be efficacious in many of these as well [ 22- 27].
I figured a "blockbuster" drug would be efficacious in more than 50percentt of the people who took it.
Proprioceptive training may be efficacious in recurrent ankle sprain prevention.
Cidofovir has been found to be efficacious in treating RRP.
This suggests that a recombinant vaccine designed to be efficacious in Africa and Asia is likely to be efficacious in South America.
AiBP was found to be efficacious in the removal of arsenic III) from water.
The use of eccentric hamstring exercise may be efficacious in hamstring injury prevention.
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