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The humanized version of Sphingomab, sonepcizumab/ASONEP (Lpath), has recently completed Phase I clinical trials in cancer, and will be advanced into Phase II safety and efficacy trials, which might be efficacious for controlling tumour growth and metastasis.
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Previously we demonstrated that porcine Mx1 (poMx1), when fused to HIV Tat protein transduction domain (PTD), inhibits CSFV propagation in PK-15 cells, but it is unknown whether PTD-poMx1 exhibits antiviral activity in other porcine lines and it is efficacious for controlling CSFV infection in pigs in China.
One systematic review evaluated acupuncture for peripheral joint OA and included 14 randomised controlled trials (RCTs) for KOA (a total of 18 RCTs); acupuncture was shown to be efficacious for pain control in KOA in sham-controlled RCTs [ 6].
Here we tested whether anti-TNF treatment would be efficacious for NPC patients.
Thus, TPM might be efficacious for treating METH dependence [ 22].
Continuous infusion of flumazenil may be efficacious for titrating the effect of sedation at the level of their CNS receptor site, allowing the practitioner further options for accurate control of sedative agents.
Anti-VEGF agents have been shown to be efficacious for treating DME.
The administration of meloxicam i.v. once prior to surgery followed by once daily oral administration for four consecutive days is efficacious for the control of post-operative pain and inflammation in horses undergoing orthopaedic surgery.
Lipton RB, Goldstein J, Baggish JS, Yataco AR, Sorrentino JV, Quiring JN (2005) Aspirin is efficacious for the treatment of acute migraine.
Neither supplement was efficacious for either indication.
Most of these interventions are efficacious for perioperitive shivering.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com