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This observation strongly suggests that booster vaccinations can only be effective when co-administered with an immunostimulating adjuvant.
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This metabolite restored sexual behavior in ∼half of the rats tested by Morali et al. [31], but was only fully effective when co-administered with DHT.
The dose of sildenafil does not need to be adjusted when co-administered with sitaxentan.
However, we show here that WNIG alone was highly effective even when co-administered with the aggressive immuno-suppression agent, dexamethasone, which affects the innate immunity [ 26].
This drug is contraindicated when co-administered with rifamycins or proton-pump inhibitors.
The plasma concentrations of pioglitazone were slightly lower when co-administered with luseogliflozin than when pioglitazone was administered alone.
For instance, the fact that a low dose of citalopram is already effective on postsynaptic targets when co-administered with a 5-HT4 agonist (Fig. 2) opens the perspective of reducing the doses of SSRI administered, in order to reduce side-effects as well.
A dose of 30 μg of ethinyl estradiol is needed for adequate contraception when co-administered with the FDC.
Consequently, clozapine is involved in significant pharmacokinetic interactions when co-administered with other drugs.
Elvitegravir exposures at 85 mg when co-administered with atazanavir/r 300/100 mg were similar to elvitegravir 150 mg.
Buprenophine's potency was increased 8.2-fold at 2-h and 7.2-fold at 4-h when co-administered with THC.
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