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Naturally, we would assume they would be more effective in samples that at some stage demonstrated CIMP but they may still be effective in samples that do not demonstrate CIMP in the later grades if CIMP was present in the precursor lesion.
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Recently axitinib was shown to possess high affinity to T315I-mutated BCR-ABL1, which may explain the high activity in patient sample 2. A small number of other drugs with various mechanisms of action proved to be effective in most samples.
Still, it could be a relatively low-effort way to help combat obesity-related disease, if it can be shown to be effective in larger sample sizes.
The proposed method was proved to be effective in evaluating reclaimed water samples in case studies.
Additionally, we used K-means clustering to segregate the expression datasets, but other clustering approaches, such as that proposed by Ruan et. al, or other commonly used clustering techniques, could also be effective in pre-sorting of samples.
In contrast to genomic scale analyses on large datasets, a refined study on a well-controlled set of samples can be effective in demonstrating the effects of particular splice-related factors.
Together, the combination of quality control methods used here should be effective in recognizing poor-performing FFPE samples and could be used to prevent unnecessary array hybridizations.
The pre-sputtering of the sample surface by the primary Au+ ion beam of ToF-SIMS may be effective in removing contamination from the sample surface.
The CRP method can be effective in balancing the sparsity of sampled vectors in DCT domain of image, and then in improving the CS sampling efficiency.
The pre-sputtering by Au+ beam could be effective in removing contamination from the sample surface.
Similarly, older NO donors such as glyceryl trinitrate administered by inhalation have been shown to be effective in reducing PAP in small clinical samples (Goyal et al., 2006).
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