Sentence examples for be effective in mediating from inspiring English sources

These grafting conditions proved to be effective in mediating EC adhesion/cytoskeletal organization on CH with DA 4% and 15%, without affecting the endothelial angiogenic potential.

More recently, immune-based therapies have been shown to be effective in mediating durable responses in cancer patients with advanced disease.

These levels of adenovirus-mediated IL-2 and IL-12 expression were effective in mediating tumour regression in a murine model of breast cancer (Emtage et al, 1999).

Cnp1-Cre mice have been described previously and shown to be effective in promoting Cre-mediated recombination in mouse embryonic peripheral nerves before the radial sorting of axons [ 23 25].

Although it is difficult to predict or control the former, our results clearly show that limiting mCrem expression may be effective in controlling tamoxifen/OHT-independent mCrem mediated recombination, although at the expense of potentially requiring higher dose or duration of OHT treatment to induce maximal recombination.

It is of interest that animal studies have shown that alosetron, a 5-HT3RA shown to be effective in IBS-D, inhibits spinal pathways mediating the response to painful colonic distension.

For example, a drug that targets CD8+ T cells would not be effective in a model in which CD4+ T cells mediate pathology.

Considering that MSC supernatant alone can be effective in treating some diseases, it is possible that MSCs themselves may not be indispensable in mediating the therapeutic effect.

Adenovirus-mediated gene delivery of VEGF121 has also been reported to be effective in improving lower-extremity endothelial function and flow reserve [ 7].

The field of lncRNA biology would benefit greatly from the development of additional approaches that are effective in distinguishing effects mediated by lncRNAs as molecular species from their effect on gene regulatory elements with which lncRNA loci are interleaved across the mammalian genome.

These findings indicate that a novel bifunctional pro-drug is effective in limiting NM mediated dermal injury.