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For a drug to be effective and selective in cancer therapy, it must reach the target with sufficient concentrations to inhibit targets and related pathways that are responsible for tumour growth and/or metastasis.
Because SLC6A14 is essential for tumour growth yet dispensable for normal development and tissue maintenance, small molecules that block amino acid import through this transporter could be effective and selective anti-cancer agents, particularly as components of rational drug combinations.
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We present results showing that CexZr1−xO2 solid solution catalysts are effective and selective for producing diethyl carbonate and could be recyclable without loss of any activity.
If the manipulation is effective and selective influence holds, the fastest responses are made when both sources have high salience and slowest when both sources have low salience.
Surface and interfacial engineering of heterogeneous metal catalysts is effective and critical for optimizing selective hydrogenation for fine chemicals.
We know that it isn't airborne, selective quarantines can be effective but blanket ones are not, and that screening and treatment are effective and panic and racism is not.
The weapon, according to a recent article by its developer, could, be effective against selective targets—such as the tanks that may be used in a Soviet attack in Western Europe.
Developing nanomaterials that are effective, safe, and selective for gene transfer applications is challenging.
This suggests the need for alternative treatments that are effective, safe and selective for the established asthma phenotypes, especially in patients with uncontrolled severe asthma.
Our study, to our knowledge, is the first one to demonstrate that lytic conjugative plasmid dependent phages can, in principle, be effective selective agents against conjugative elements and thus the spread of drug resistances even when the bacteria are under sublethal antibiotic selection favouring the horizontal spread of resistance.
The MOF having ability of hydrogen-bonding donor and acceptor were proved to be effective for the selective removal of gases [5].
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CEO of Professional Science Editing for Scientists @ prosciediting.com