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These results can be easily rationalized on the basis of crystal structure considerations.
This result also allows for an understanding of the existence of isothermal isofield "windows" where the relaxations can take place, and the experimental results found in quite different systems can be easily rationalized in this way.
Whereas traditional programming is rational in the sense that it provides the program with a rationale by its reliance on subjective method and problem solving, these new techniques of "dark programming" do not produce any rationale; moreover, the results are not restricted to be easily rationalized.
That relative specificity is functionally relevant can be easily rationalized if it correlates with differential gene expression.
The cost of such development and utilization can be easily rationalized based on the patient and societal costs of end-stage renal care of chronic dialysis patients.
This effect can be easily rationalized considering that in the latter condition, substrate binding to ADP-bound state becomes dominant and the system cannot exploit the time-scale separation in binding/unbinding kinetics to achieve ultra-affinity.
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This derelict rundown of the military was easily rationalized at the time.
This is easily rationalized because rapid substrate dissociation from the ligase provides less time to build ubiquitin chains.
In general, the proteins exhibit functional alterations that are easily rationalized in the context of a recombinational system that must simultaneously deal with large numbers of double strand breaks in cells where metabolic processes might be compromised.
The observed activity of the two variants with only one of either of the active site cysteines is easily rationalized in view of the fact that the escape mechanism is not necessary for the enzyme to function in assays with peptides, as described elsewhere (10).
While each of these individual steps are easily rationalized by the ratio of bromide:phenoxide substituents at the boron center, the overall barrier trend of 24.8, 25.3, and 22.2 kcal/mol for cycles 1, 2, and 3, does not dominantly arise from one of the three fundamental reaction steps (i.e. none of these individual reaction steps govern the rate for each cycle).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com