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Although MS-based technology may not have the resolution to identify proteins in very small quantities or metabolites, such as high performance liquid chromatography (e.g., [21]), we anticipate that this technology will identify proteins that can be easily quantified with other platforms, such as enzyme-linked immunosorbent assays (ELISA).
With multiple target loci for which the efficiency of Cre-medated recombination can be easily quantified with AP histochemistry - including Brn3a, Brn3b, Z/AP, and Fz5 - we have consistently observed a decline in efficiency with increasing postnatal age when tested with a variety of CreER lines, including R26CreER, NFL-IRES-CreER, and ChAT-IRES-CreER (our unpublished observations).
The rocking isolation effect can be easily quantified with regard to the moment capacity of the rocking foundation, being therefore potentially useful for the estimation of seismic demand in design.
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Sprouting angiogenesis can be easily quantified by image analysis after immunostaining of endothelial cells with CD31 pan-endothelial marker.
Although it is difficult to saturate the L22P mutant with substrates, an apparent catalytic efficiency (kcat/ KM,dCTP) can be easily quantified.
Such companies take risks that often cannot be easily quantified.
Why do we emphasize math so much and disregard things that cannot be easily quantified?
In the case of buying bulk paper and the like, savings can be easily quantified.
While the costs involved in this redesign can be easily quantified, the benefits cannot be easily estimated.
In principle, the structural information can be easily quantified [14].
These can not be easily quantified but a good first take is that those who have the most are those who have clearly gained the most from having a society with a healthy educated workforce & a decent modern infrastructure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com