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Also, the significantly over-represented molecular functions of human calpain substrates are protein activity and various molecular binding, which can be dynamically regulated by cleavage (Supplementary Table S3).
The splicing pattern might be dynamically regulated by external stimuli; in fact, most cellular signaling pathways that change gene transcription also alter groups of alternative exons [90].
Both the development and ongoing functions of the placenta may be dynamically regulated by environmental factors, including nutrient status and tissue oxygenation [19].
Moreover, hypoxia increases the levels of Snail protein through HIF-1/Twist-dependent down-regulation expression of FBXl14, which promotes Snail ubiquitinylation and proteasome degradation, showing that Snail protein stability could be dynamically regulated by a GSK-3β/β-TrCP1-independent process [49].
We hypothesized that these genes would be dynamically regulated by age and by social experience based on evidence for alterations in neural physiology with age and experience [20], [21], and for genetic variation in age-related male reproductive physiology [22], [23].
The PHF1 epitope (comprising pSer396 and pSer404) appears to be dynamically regulated by stress.
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By using the state transformation of nonlinear systems, the problem of designing controller can be converted into that of designing a dynamic parameter, which is dynamically regulated by a dynamic equation.
A very recent study reported that Gomafu expression is dynamically regulated by neuronal activity; depolarization in cultured neurons leads to the rapid down-regulation of Gomafu within 30 min.
We suggest that the backprojection has important functions normally that are dynamically regulated by nonprincipal cells of the dentate gyrus.
In the last step, variable time delays and weights are dynamically regulated by ATNN and the output of ATNN can be obtained as a multi-step-ahead prediction.
It may be of less importance, however, for transporters that are dynamically regulated by other mechanisms, for example for insulin-induced cell surface expression of GLUT4 (James et al. 1989).
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