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It is thought this could be due to single gene effects, whereby the resistance gene and QTL are allelic, or by the effects of clusters of genes.
The reasons for this failure are unknown, but may be due to single mutations that up-regulate efflux pumps causing multi-drug resistance (Gottesman et al. 2002).
The four ambiguities were found to be due to single base pair insertions or deletions in FSL R2-574 relatove thethe F2365 genome.
Here we aimed to investigate the reason for this failure, hypothesising that it might be due to single amino acid variations in conserved epitopes.
In any case, the putative regions of association on BTA 13 and BTA 2 may be due to single quantitative trait loci in LD with the regions of the SNPs, or they may indicate the presence of more than one quantitative trait loci in these regions.
In addition, the twice-a-day and thrice-a-day dosed medications were more potent than once-a-day dosed medication, which may be due to single dose of large amount of drug exceeding the capability of absorption in gastrointestinal tract.
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Most of these substitutions are due to single nucleotide changes.
Most of the infections were due to single HPV types with only four cases due to multiple infections.
These gaps were due to single blocked reactions or reaction cascades implying that current information concerning the metabolism of these amino acids is fairly complete.
Although there where 1420 answered questionnaires, the differences between 1398 and 1411 were due to single parent families (17 in total) b.
Some of the Knops blood group polymorphisms, which are due to single nucleotide changes in the CR1 gene (Ref. 222), may affect malaria susceptibility (Refs 223, 224).
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