Sentence examples for be driven to differentiate from inspiring English sources
MUC1 is newly expressed in the cells underlying the shed cells, suggesting that the suprabasal cell layer contains progenitor cells that can be driven to differentiate into luminal cells, replacing the shed cells and maintaining the barrier.
ESCs are karyotypically normal, self-renewing and pluripotent cell lines derived from the mammalian blastocyst that can be driven to differentiate toward all the three germ layers.
As has been proposed for monocyte/macrophage precursor cells that can be driven to differentiate into dendritic cells or osteoclasts, the acquired changes of neutrophils reported above could represent an intermediary phenotype observed during the transdifferentiation of these cells [ 46].
These leukemic DCs contained ITD mutations and could be driven to differentiate into mature mDCs or pDCs in vitro upon culture with cytokines, but they were not fully capable of secreting several cytokines [ 14].
Primitive myeloid leukemic cell lines can be driven to differentiate to monocyte-like cells by 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3), and, therefore, 1,25(OH)2D3 may be useful in differentiation therapy of myeloid leukemia and myelodysplastic syndromes (MDS).
Once BM-MSCs are driven to differentiate toward one cell type, another cell fate is simultaneously inhibited [ 21].
Furthermore, CD24+ cells are driven to differentiate in response to intra-tumor stimuli into a distinct CD24− cell population, thus, creating intra-tumor heterogeneity.
Employing identical culture conditions used to induce ES and iPS differentiation into hepatocytes, Muse-AT cells were also driven to differentiate into hepatocyte-like cells (Figure 4C) [26].
Many cancers appear to be driven by stem-like cells that self-renew, differentiate to yield heterogeneous progeny and survive adverse microenvironments (Dalerba et al, 2007).
