Sentence examples for be driven through activation from inspiring English sources
PI3K/AKT signalling pathway activity can also be driven through activation of erbB3 and erbB4 receptors via their ability to directly recruit the p85 regulatory subunit of PI3K [ 20, 21].
Evidence is emerging to suggest that aseptic loosening of total joint replacements is driven through implant debris activation of the inflammasome leading to locally elevated levels of inflammatory cytokines [ 74].
Results have been driven through statistical analysis.
Smad1/5/8 activation can on one hand be driven by BMPs through the ALK1/2/3/6 receptors.
Indeed, ERK activation is directly linked to Ras through the Raf-MEK pathway, whereas Akt is a downstream effector of PI3K, whose activation can be driven not only by Ras but also by diverse inducers [ 49– 51].
This induction occurs through the evolutionarily conserved heat shock transcription factor Hsf1. How the cell senses changes in ambient temperature, thus triggering Hsf1 activation, was thought to be driven by the accumulation of denatured proteins (9).
Tumour hyperglycolysis is driven by activation of hypoxia-inducible factor-1 (HIF-1) through tumour hypoxia.
Our data provide strong evidence that constitutive overexpression of IFITM1 is driven by IFNα through activation of the canonical signaling pathway and that STAT1 and STAT2 play a critical role.
