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These data suggest the risk of ER-positive tumors that has been shown to be driven by reproductive factors in epidemiologic studies also has a genomic basis based on the constituents of the ER gene regulatory network [ 46, 47].
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First, our results demonstrate how phenotypic evolution can be driven by selection against reproductive variance.
Additionally, speciation may also be driven by Wolbachia-induced reproductive incompatibility.
For male-biased genes, this pattern appears to be driven by gene expression in reproductive tissues [ 60] and an excess of X-linked male-biased genes in somatic tissue (head) has been reported [ 32, 60].
The evolution of these behaviors is hypothesized to be driven by female choice because of the larger reproductive investment into eggs relative to sperm.
Our result shows that positive selection is significant in both datasets, which consistent with other reports referring that the rapid divergence of the reproductive genes may be driven by positive selection [ 43, 58].
The chromosomal bias in male reproductive tissue-specific genes could be driven by either mechanism.
They may simply be driven by greed.
Don't be driven by necessity.
Be driven by the future.
This again indicates that the transcriptional landscapes of non-reproductive mycelia versus protoperithecia are rather different, and that overall transcription in sexual mycelium is driven by the non-reproductive hyphae that make up the majority of this sample.
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