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Coding variation outside these regions is negligible, a pattern thought to be driven by intra- and interlocus recombination.
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Accumulating evidence suggests that treatment failure in cancer may be driven by intra-tumour heterogeneity (ITH), and branched tumour evolution involving genetically distinct sub-clones [ 2].
Within this body of literature, the intergenerational transmission of behavior is considered to be driven by intra-familial socialization processes that occur during childhood and adolescence (Hendershot 1969; Thornton 1980; Axinn et al. 1994; Murphy and Wang 2001).
We also provide evidence that evolution of these genes is driven by intra- and intergenic recombination, thereby modulating the number of LRRs in protein and generating chimeric genes.
Thus, whilst the effects of high-dose nitrate supplementation might be attributed, at least in part, to mitochondrial biogenesis, it appears that at lower doses there is nevertheless an enhanced capacity for FA oxidation which is driven by intra-mitochondrial changes.
Next, we tested whether these differences could be driven by pre-copulatory intra-sexual selection (male-male competition).
The constant volume assumption was validated post-hoc by estimating the intra-stereocilia axial fluid flow per cycle (Poiseuille approximation) that would be driven by the flexoelectric perturbation in the intra-stereocilia pressure (Laplace approximation), and confirming that the axial flow is many orders of magnitude less than the stereocilia volume at frequencies addressed here.
They may simply be driven by greed.
Don't be driven by necessity.
That will be driven by people.
Be driven by the future.
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