Sentence examples for be driven by intestinal from inspiring English sources
In AID knock out mice, Peyer's patch hypertrophy has been shown to be driven by intestinal bacterial overgrowth (Fagarasan et al, 2002).
As pathology is driven by intestinal bacteria 40, 57, we conclude that TLR2-mediated stimulation of APC by microflora constituents is mechanistically redundant for the induction of colitogenic T-cell responses.
Inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn's disease, are widely believed to be driven by inappropriate responses to the intestinal microbiota [1].
This knowledge imbalance is exemplified in Crohn's disease (CD), a chronic, relapsing-remitting form of inflammatory bowel disease thought to be driven by aberrant immune responses to intestinal bacteria.
We have shown that sFRP1 transcription can be driven by β-catenin in normal intestinal epithelial cells, but that premalignant colorectal adenomas contain greatly reduced levels of sFRP1 compared to matched normal mucosa and this is accompanied by increased methylation at the sFRP1 locus.
Normal development and function of murine, and by inference human, intestinal T cells is critically dependent upon microbial cues, 18 suggesting that many of the pathways we have identified will be driven by interactions with the gut microflora.
Inflammatory bowel disease (IBD) is a chronic inflammation of the intestinal epithelium that is driven by the intestinal immune system, oxidative stress and the loss of tolerance to the luminal microbiota.
