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These data further suggest that clonal architecture might be driven by genetic heterogeneity of propagating or 'stem' cells.
Thus, natural selection, acting primarily on our Pleistocene hunter-gatherer forebears, has led men's preferences to be driven by genetic makeup to optimize the chances of their genes being preserved.
Epigenetic differences might be driven by genetic differences as well as by other environmental and dietary factors.
The population level obesity epidemic is unlikely to be driven by genetic factors and at an individual level genetic manipulation is currently not possible.
Clonal expansion is traditionally thought to be driven by genetic and epigenetic changes inherited by cell division [ 30].
In our experiment, the differences in allele frequencies between the two lines could be driven by genetic drift and selection.
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Here the process of adaptation is driven by genetic variations among individuals that become adapted to that is, have greater success in a specific environmental context.
The progression of cancer through stages that guide a benign hyperplastic epithelial tissue towards a fully malignant and metastatic carcinoma, is driven by genetic and microenvironmental factors that remodel the tissue architecture.
One would expect that if the miRNA expression heterogeneity in single cells was driven by genetic differences between cells, large variation would be manifested similarly between single-cell clonal populations because each clone was derived from a single cell and cells within a clone share the genetic variations present in the initial single cell.
Tumor progression is driven by genetic mutations, but little is known about the environmental conditions that select for these mutations.
The fundamental role that we can bestow to these categories suggests that human evolution may have been driven by genetic changes that can entail great phenotypic changes.
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