Sentence examples for be driven by binding from inspiring English sources

At the linear DNA level, gene activity is believed to be driven by binding of transcription factors, which subsequently recruit the RNA polymerase to the gene promoter region.

We therefore hypothesized that some or all of the cis-regulation of SATB2 critical for craniofacial development may be driven by binding of SOX9.

The specificity shift appears to be driven by binding forces and restrictions that dictate which end of a peptide each enzyme can accommodate; the enzyme chemistry for both is the same.

These results demonstrate that residues seemingly only involved in general DNA binding are important for catalytic activity and imply that base excision is driven by binding energy provided by the entire substrate interface of this novel DNA binding architecture.

Authors' response: (i) Every stage of RNA metabolism is driven by binding of RNA binding proteins (RBPs) through RNA binding domains.

Allosteric regulation is driven by binding of an effector molecule to an allosteric site, that is, to a site topographically distinct from the protein active site.

The stepwise assembly of TβRI and TβRII into a TβRI2-TβRII2 heterotetramer is driven by binding of TβRI to a composite TGF-β/TβRII interface.

The organism specific recognition of protein-RNA complexes may be attributed with the following perspectives: (i) every stage of RNA metabolism is driven by binding of RNA binding proteins (RBPs) through RNA binding domains.

The accumulation of rucaparib into PARP-1 null MEFs was similar to that of their wild-type counterparts (data not shown); thus, it seems unlikely that accumulation is driven by binding to PARP-1.

12 The binding site of neuraminidase is a conserved region in different variants of influenza A and B. The key step of viral attack and multiplication in the host cell is driven by binding of viral neuraminidase to sialic acid on the human cell surface.

The promoters of genes in the module shown in Figure 6A were overrepresented for the W box (de Pater et al., 1996), suggesting that the dependent co-expression is driven by binding of TFs from the WRKY TF family (Eulgem et al., 2000), known to play a key role in regulating plant stress responses (Chen et al., 2012; Eulgem and Somssich, 2007).