Sentence examples for be driven by alterations from inspiring English sources
In parallel with those observations, many lines of evidence suggest that cancers may be driven by alterations that are epigenetic in nature, that is, they do not alter the primary DNA sequence (McDonald et al, 2011; Timp and Feinberg, 2013).
The changes in EYA3 expression that we report are unlikely to be driven by alterations in the duration of the nocturnal melatonin signal, as this hormone continues to report the prevailing photoperiod, irrespective of circannual phase [ 10].
The mutations of these genes seem to have different impacts on cellular functions, manifesting as unique MDS phenotypes and suggesting that MDS phenotypes may be driven by alterations in splicing machinery.
An increased number of circulating plasma cells and the presence of autoreactive T and B cells in the sera of patients with SLE suggest that the disease might be driven by alterations in DCs.
Consistent with our prediction that attentional training would primarily be driven by alteration of frontal function, no such effect was apparent in the amygdala, even when using an ROI analysis (Supplement 1).
This rapid relapse is driven by alterations in the Aurora B signaling pathway that hyper-stabilize k-MT attachments and is reversible following UMK57 removal.
Cancer development is driven by alterations in both genetic and environmental factors.
This component is driven by alterations in signaling molecules, such as CBL, CBLB, FLT3, JAK2, LNK, MPL, NF1, PTPN11 or RAS.
The pathogenesis is driven by alterations in the immune system and is associated with high neutrophil counts related to a specific delay in apoptosis [ 1].
Overall, the 2C results indicate that TCR cross-reactivity need not be driven by dramatic alterations in the TCR-binding site, the existence of different interatomic contacts within the interface notwithstanding.
However, there are several indications that central alterations in nociceptive processing can be driven by peripheral tissue alterations [ 76] and peripheral nociceptive input [ 80, 81] also in the chronic stage of a pain condition.
