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Colistin pharmacokinetics are expected to be dramatically altered in critically ill patients, because they are frequently prone to large swings in distribution volume, fluctuations in renal clearance, and variable protein binding.
It is known that the physiological function of in vitro cultured cells could be dramatically altered in response to physical stimuli including electromagnetic field, mechanical force and heat treatment [7].
Although the vast majority of environmental factors cannot alter DNA sequence, epigenetic processes can be dramatically altered in response to environmental factors from nutrition to temperature (Skinner 2014a).
14, 18 Specifically, the two miRNAs miR-103a-3p miR-103a-3p miR-103a-3png et ands miR-143-5p miR-143-5p miR-143-5pered to be dramatinally altered in the US cohort.
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This pattern was dramatically altered in alcohol-fed mice, marked by a 49 51% ratio and the absence of a distinct peak.
These bodies were dramatically altered in composition when the Sun accreted enough mass to trigger the ignition of thermonuclear fusion in its interior, releasing vast amounts of energetic electromagnetic radiation.
While chow-diet fed mice had a normal 24:76% ratio of feeding activity, with a peak in the early night, this pattern was dramatically altered in both liquid-diet groups: mice had a 43 57% ratio, and an absence of a distinct peak.
ABC's fortunes were dramatically altered in February 1953, when the FCC cleared the way for UPT to buy the network.
Gene expression was dramatically altered in lymphomas, yet paralleled data from T-cell lymphomas induced by other mechanisms.
In summary, we have discovered significant microRNA expression in human mature erythrocytes, which is dramatically altered in HbSS erythrocytes and their defect in terminal differentiation.
There is precedence for such a paradigm; several studies have demonstrated that bacterial community composition is dramatically altered in diseases such as obesity and periodontal disease [8], [31], [32] and that these changes are associated with altered consortium functionality [9].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com