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Testing for safety and side effects would still have to be done on human volunteers because that requires exposing people only to the drug, not to the lethal agent.
Conventional virus isolation by cell culture can be done on human embryonal tracheal cells.
It is apparent, therefore, that further work needs to be done on human pulmonary artery rings to elucidate if conditions other than prestimulation or preexisting lung disease (and associated pharmacological agents) play a role in varying the response to hypoxia.
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"Not all of the experiments they did could be done on humans but enough could have been done to confirm the presence of similar channels," he said.
Sometimes those who seek to outlaw use of animals in research argue that testing new treatments should be done on humans, not animals.
The amount of experimental work which has been done on human beings is, unfortunately, very large indeed.
Not enough work has been done on human variation.
Since many existing preclinical AELs are based on commercial culture medium with or without nonhuman serum, they may not authentically reflect the clinical situation in human patients, and little research has been done on human plasma exposure in in vitro culture-based bioreactors.
Extensive study has been done on human activity recognition with wearable sensors [7 11].
The experiments were done on human acute T-cell leukemic CCRF-CM cell line.
On the other hand, our experiments were done on human DCs infected by NDV.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com