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Though, this view is in harsh contrast with observations that PrP seems to be dispensable for normal development and health of individual mammals [14], [15].
Bmf seems to be dispensable for normal embryonic development and organogenesis.
However, the p120-catenin binding site of E-cadherin appears to be dispensable for normal Drosophila oogenesis and embryonic development [83].
These results suggest that AGO18 may be dispensable for normal growth and development of rice, but is required for defense against RSV infection.
c-Myc appears to be dispensable for normal liver growth during the postnatal period, restoration of liver mass following partial hepatectomy and recovery from fasting.
Preliminary analyses of the mammary ductal outgrowth in these strains has revealed that a functional ILK is required for normal mammary gland development whereas a functional beta-1 integrin appears to be dispensable for normal mammary gland development.
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Camargo and colleagues initially observed that YAP1 overexpression is sufficient to cause severe abnormalities in the skin of mice[64], and later reported that YAP is essential for normal skin homeostasis by regulating the epidermal stem cell pool, while MST1/2 are dispensable for normal skin biology[82].
Our results indicate that CD177 is dispensable for normal neutrophil development in mouse bone marrow or distribution within secondary lymphoid tissues, which agrees with the observation that up to 5% of individuals have normal neutrophil counts and function with no detectable CD177 expression (Matsuo et al., 2000).
We conclude that Geminin is dispensable for normal neurogenesis during most of embryogenesis and in adulthood.
Using these mutants we showed that Mkk4 is dispensable for normal development and for host resistance to systemic bacterial infection.
These results suggest that IKKβ is dispensable for normal development, morphogenesis and differentiation of the corneal epithelium.
More suggestions(15)
be dispensable for SLP65-controlled
be important for normal
be high for normal
be dispensable for p53-dependent
be crucial for normal
be necessary for normal
be insufficient for normal
be dispensable for TCR-induced
be dispensable for somatic
be understandable for normal
be suitable for normal
be fine for normal
be available for normal
be dispensable for p53-mediated
be steady for normal
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