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The number of SNPs to be discovered by sequencing additional strains was estimated as described64.
Reassortment events such as this can only be discovered by sequencing multiple virus segments.
Therefore, the entire gene pool can be fully sampled by sequencing a small set of representative isolates, and the number of new genes to be discovered by sequencing additional genomes will quickly approach zero.
The expected number of new genes to be discovered by sequencing additional L. monocytogenes strains, and the sizes of the core and pan-genomes, were estimated using methods adapted from Tettelin et al. [ 24].
We demonstrated here that high numbers of genome-wide SNPs can be discovered by sequencing total genomic DNA of a complex genome with NGS platforms without a reference genome sequence.
According to [ 26], the number of new genes n expected to be discovered by sequencing an Nth genome was modeled by the power law function n = κN- α, and the number of pan genes also by a power law n = κN γ.
Similar(54)
EBV microRNAs (miRNAs) were discovered by sequencing libraries of small RNAs generated from several EBV-positive cell lines.
As new disease genes are discovered by sequencing hundreds of thousands of people, a swelling population will undergo specific panels of tests of 15 genes or more.
In studies on DNA methylation in rice and corn, functional genes related to stress tolerance and heterosis have been discovered by sequencing differentially-methylated fragments (Hua et al. 2005; Zhao et al. 2007).
Additional SNPs were discovered by sequencing the transcriptomes of T. aestivum cv.
Another element, IS _map02, is a MAP specific insertion sequence that was discovered by sequencing the K-10 genome.
More suggestions(18)
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