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Conventionally, immune cells can be directly modified using CAR viral particles.
The resulting condensed polyplexes generated from the microsponges can be directly modified using the versatile approach of layer-by-layer (LbL) assembly, for which key design parameters such as layer components, layer number, and layer order, make this platform a valuable option for tuning the properties in therapeutic nanoparticle delivery systems.
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Finally, secreted scFvs could be directly modified via EPL, immobilized onto surfaces using SPAAC, and employed to bind their respective antigens.
The modifying vectors pCmaSpHomBBeloHomA (pBACLinkSpAB) and pCmGmHomCbeloHomB (pBACLinkGmBC) cannot be directly modified by other investigators for use with other BACs.
Finally, using our mathematical model, we simulated a situation in which the chromatin dynamics were directly modified by TSA.
Interestingly, the abundance of a transcript is directly modified by polymorphisms in regulatory elements [ 161].
The method was modified using immunoprecipitation (IP) of TTR directly from crude CSF to minimize ex vivo protein artifacts [ 20].
DNA samples were modified using EZ DNA Methylation Golden Kit Zymo Researchh, Orange, CA).
Thirdly, SFAs especially palmitic acid, as well as their metabolic intermediate acetyl-CoA, can be directly used as substrates to modify proteins, in the forms of palmitoylation and acylation.
Therefore PRR's were directly estimated, using a modified Poisson regression approach [ 15].
Phage can be directly used as a probe when it is modified to display disease-related antigens on its surface (Kierny et al. 2012).
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