Sentence examples for be difficult with existing from inspiring English sources

Effective removal of these pollutants can be difficult with existing water-treatment facilities.

Capturing change involving similarly complex interrelationships between cultural elements in a population of agents would be difficult with existing modeling strategies.

Studying these haplotype patterns can be difficult with existing forward-in-time simulators because detailed information about the mosaic haplotype structure of individuals is not readily available, and must be inferred from the output sequences of the simulation and/or stored recombination event data.

Detection of the NV GII strain is difficult with existing RT-PCR primer sets (GII-F1/R1/F2, SRII-1/2/3) because of the continuous variation of the strain [ 26, 27].

Assessing cost differences occurring as a result of introducing IMCU beds can be difficult, with the existing literature using the typical bed-day cost algorithm, which does not factor in the reduced acuity and cost of patients as they move through the ICU and hospital, such that an ICU day cost before they move to the ward is very similar to the first day on the ward cost [ 26].

Since the detection of endogenous Fmn1-IV has been difficult with the existing reagents, we generated an EGFP-Fmn1-IV fusion knock-in mouse in which the fusion protein is driven from the endogenous promoter (Fig. 1A).

Masks of zero population are another alternative, though aside from waterbodies (for which reliable and sufficiently high resolution data is rare), deciding what constitutes an area of no human habitation is difficult, with settlements existing around the world in national parks, industrial areas and deserts for instance.

"It's difficult with Margate.

The sale was especially unusual because the Chinese missile defense system, known as the HQ-9, would be difficult to integrate with existing NATO equipment.

When a salient object shares a similar colour with the background, it is difficult for existing RGB models to extract saliency.

The SCF process is able to microencapsulate many materials that are difficult to treat with existing techniques.