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Homolog identification can be difficult when comparing genomes across great evolutionary time as a result of sequence evolution and paralogous duplication events within a lineage.
Sensitivity and specificity are "two sides of the same coin" and should always be considered together, which can be difficult when comparing tests; if one test has high sensitivity and another high specificity, which is better?
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A realist acknowledges that the problems facing today's world are difficult when compared with those bygone, idealistic days at Wellesley or Tara, which may have been much more carefree.
In addition, although some of these catalysts have high TOF (e.g., solid silica based sulfuric acid [5] or SnIV TNH2PP)(OTf)2@CMP [11]), its preparation is difficult when compared with SANM.
Tying can be difficult when using wires.
It's difficult when you compare yourself to others who are more successful and you internalise the fear or worry that you're not good enough, or not where you're supposed to be.
However, providing knowledge about choices can be more difficult when compared to DAs that offer relative risk or research based outcome comparative information about choices.
"It's difficult when you're 45 compared to when you're 29, but you still have to run as fast as you can.
Second, it is known that subjects rate uphill walking as being more difficult when compared to horizontal running at similar metabolic rates and that "perception of effort" during exercise can clearly alter exercise hyperpnea [ 13, 14].
The series was extremely difficult when compared to other RPGs of the time, possibly because they were modeled after pen-and-paper role-playing games of similar difficulty.
Controller design for unstable processes is relatively difficult when compared to stable processes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com