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But finding opportunities for reuse can be difficult when building a large software system with pieces of a large previous system.
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However, building a reliable ANN model requires sufficient training data, which may be difficult when data are collected from litre-scale experiments.
Building evidence to manage patients with this combination could be useful because non-steroidal-anti-inflammatory-drugs (NSAIDs) might interfere with blood pressure control and keeping up an active life style can be difficult when suffering from osteoarthritis.
Tying can be difficult when using wires.
"Everything was difficult when it started.
Because it was difficult to simultaneously incorporate every intermediate biological process of inflammatory response, reasonable assumptions must be made when building a mathematical model.
A crucial and difficult step when building a regression model is the selection of variables to be included in the final model from a set of plausible and meaningful variables [ 3].
Such measures also reduce the harm of other unwanted incidents, such as fires, but can sometimes be difficult to install in existing buildings, especially when the buildings have historical value.
Because of its proximity to the area's transportation hub, it might be attractive to a commercial developer, although it would be difficult to justify an office building there when 10 million square feet of space is scheduled to go up across the street over the next decade.
Getting a good doctor and building a relationship with them can be difficult so I find it frustrating when my doctor changes during my treatment.
"The set was difficult to build and I liked the accomplishment when I had finished building and could play with it".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com