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Of course, it can be difficult to target voters who have never participated before, which is precisely why strategists often advise against it.
But Isis has established secure safe havens, including some in neighbouring Syria, which will be difficult to target, experts say.
However, since these signaling kinases are involved in the regulation of many physiological processes, it would be difficult to target them without unpredictable side effects.
The studies indicate an important role of amino acid residues outside of the active site, which would be difficult to target by other methods.
Unlike Libya's vast desert spaces where military vehicles could be identified and attacked, Syria is densely populated, and much of the fighting is concentrated in urban neighborhoods where it would be difficult to target loyalist forces without causing civilian casualties.
Furthermore, Notch receptor/ligand and NICD/CSL complexes may be difficult to target with small molecules.
Similar(50)
Triple-negative breast cancers (TNBC) lack HER2, ER, and PR, so they are difficult to target and no molecular targeted therapies exist for these breast cancers.
Ads are difficult to target: space on billboards and in newspapers is seen by lots of shoppers.
If Stuxnet was aimed specifically at Bushehr, it exhibited one of the weaknesses of cyber attacks: they are difficult to target and also to contain.
AMBER alerts seem to generate the most complaints, followed by flash-flood warnings, which are difficult to target because of topographical variations even within a small geographic area.
CERA's Mr Yergin says it is difficult to target all the oilfields, pipelines and export terminals that matter in the area.
More suggestions(18)
be difficult to orient
proved difficult to target
be difficult to commercialize
be afraid to target
be difficult to smell
be difficult to achieve
be legal to target
be difficult to deal
be difficult to forget
be wise to target
be difficult to draw
be difficult to meet
be difficult to check
be difficult to quit
be difficult to resist
be difficult to sell
be difficult to replace
be difficult to stay
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com