However, it is difficult to tailor the ideal dose for an individual patient.
Clinicians suggested that it was difficult to tailor care to each woman given the required checking, education and documentation that had to be undertaken during relatively short hospital stays.
It is difficult to tailor the kinetics of drug release because of many factors that affect this process; however, copolymer chain microstructure should be taken into account as an important parameter that influences copolymer degradation and drug release process.
By 'complex intervention' we mean that there are many active components, which may combine to provide outcomes greater than a sum of its individual parts [ 11, 24]; that may involve complex mechanisms for delivery; may be difficult to replicate (tailored to individual); and may be influenced by the environment and social context.
This may be alleviated with a complex sequence design tailoring the refocusing pulses that may be difficult to achieve within a short TE.
In projects with high numbers of single sessions, especially those due to contextual reasons that are difficult to influence, tailored single-session counselling should be offered.
But this might not be such a desirable outcome because it will be exceedingly difficult to tailor one that really fits.
Our study further suggests that it is very difficult to tailor the appropriate antibiotic prophylaxis only by monitoring flora from oropharynx, airways, or PEG wounds.
However, at the assembly site of these large structures, it is difficult to develop a work environment tailored to the robot, and the introduction of robots has not progressed".
Yet, as Bosch notes, 29 in many cases it is difficult to assess whether such tailoring was done based on a priori barrier identification, and explicit use of theory to match the intervention to the identified barriers.
