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Unfortunately, even with the supplemental information provided by analyzing compartment-specific metabolites, it may still be difficult to statistically distinguish different configurations of the metabolic map [38].
This may only be addressed in a larger study, but it may be difficult to statistically differentiate the effect of luminal L-lactate on outcome from the effect of hyperlactataemia, because the latter is an independent predictor of mortality [ 13- 17].
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However, regional policies regarding innovation is often limited by decelerated decision making process which is often based on outdated qualitative information and data which are difficult to statistically analyze.
And since we are busy streaming these shows, it is difficult to statistically demonstrate their popularity amongst millennials.
It should, however, be noted that differences in bacterial growth smaller than half log are difficult to statistically validate.
Furthermore, it is difficult to statistically analyse differences in Snellen visual acuity following treatment, especially at low levels of vision.
Due to this variation in sperm head shape, it was difficult to statistically determine differences between the breeders, subordinates and dispersers in terms of sperm morphology.
The dependence structure among these random variables may be difficult to estimate statistically and is thus ignored in many practical applications.
It would be difficult to show statistically significant relationships with such low frequency events.
High-order interactions with non-additive effects can be difficult to comprehend statistically and perhaps even harder to tie back to biology.
Given the heuristic nature of key steps in standard phylogenomic workflows, the relevance of alignment scores to homology can be difficult to assess statistically [ 24].
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