Of course, there could be a cognitive bias in these responses as it must be difficult to state you would not want life saving treatments or that you have a poor QOL.
We were able to confirm TRAP-positive multinuclear cells on day 3 but the cells were not so large and it might be difficult to state that these cells were mature osteoclasts.
If gloves coated with PHMB may have caused such physical effects, our results would still be valid; however, it would be difficult to state that the observed effects were solely the result of an antibacterial mode of action.
In addition, it can be difficult to state guidelines that can be patient specific when multiple parameters might be used in the decision (e.g. age, comorbidity state, actual number of nodes, tumor size, hormone receptor status, histologic grade, and additional pathologic laboratory evidence).
However, a temporal threshold should be set, and GMI results obtained within this threshold may be considered to be associated with the specific IPA; in contrast, it would be difficult to state with certainty whether the GMI result is related to the specific IPA for results obtained beyond this threshold.
Changes in global trade, migration, tourism, agricultural techniques contribute to climate change and it will be difficult to state which are the most important driving forces to change [ 12, 13].
It is difficult to state the boundary between 'good' and 'bad' predictions for the problem of protein backbone dynamics predictions.
It was difficult to state unequivocally what the author was trying to convey "beyond revealing his personal contempt for the Murdoch empire and his own history of those who have been engaged in its service," Page said.
Because the principles employed by various writing systems vary greatly and because the languages they represent are organized so differently, it is difficult to state any general principles of the evolution of writing systems.
