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But killing large numbers of people with chemical weapons would require a big stockpile of deadly substances which would be difficult to accumulate without attracting suspicion.
Given the relatively low mutation rate of SNPs, even 250 SNPs can be difficult to accumulate in systems where bacteria introduction is relatively recent (see examples given in the methods section).
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When the stacking fault energy is too low, the grain size lies below 15 nm after SPD processing and the stacking faults are saturated so that it is difficult to accumulate dislocations and deformation twins during the subsequent tensile testing.
In the regions of extensively hydrated plate boundaries that produce abundant clay minerals such as chlorite, a large elastic strain is difficult to accumulate and does not generate large thrust earthquakes, whereas the regions escaped from the hydration reactions could result in a strong mechanical coupling that acts as a seismic asperity.
Moreover, acetyl-CoA is native to E. coli in large amounts, whereas branched-chain substrates for FabHB are difficult to accumulate in E. coli [ 46, 55].
The case numbers were difficult to accumulate in a short time because most blunt chest traumas could be treated with non-surgical methods and only about 10% of blunt chest injuries will evolve to retained pleural collections where surgical interventions should be arranged.
Some points accumulated will be difficult to reverse, while other points gained and lost by certain types of items work well in combination with point adjustments of other items.
First, nonrecombining portions of the genome tend to accumulate repetitive sequences that can be difficult to sequence and map.
Furthermore, the plants accumulating high value diterpenoids may be difficult to grow efficiently.
Phylogenies of rapidly evolving pathogens can be difficult to resolve because of the small number of substitutions that accumulate in the short times since divergence.
But that could be difficult to prove according to former Denver district attorney Norm Early who noted that Holmes spent months accumulating weapons and ammunition.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com