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However, the distinction between ADC and SqCC may be difficult in small FNA specimens.
Although the documentation of quality may be difficult in small patient series, there has definitely been no "Bristol cases" [ 2] in this patient population.
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This is difficult in small animals.
While biopsy of these highly vascularized lesions under field conditions is possible, it is difficult in small passerines, where creation of an open wound may lead to subsequent secondary bacterial infections.
Determination of vessel diameter is difficult in small capillaries, and consequently the relative error in measurements may be greatest in small vessels.
Given the enormous amount of genomic information available, utilizing the HapMap LCLs as our discovery set allowed us to generate this new and novel phenotype, which would be difficult in a smaller or less homogenous sample set.
The positive correlation between the rate of adaptive evolution and Ne implies that detecting the signature of adaptive evolution using MK approaches is likely to be difficult in species with small Ne because they are expected to have undergone low levels of adaptive evolution.
As acknowledged by the authors, it is difficult in a small study to control for center-specific effects, especially when early study termination precludes any meaningful subgroup analyses.
Things have always been difficult in Corinto, a small town in Cauca province that has lived for decades in the crossfire between the Farc and the military.
However stenting is difficult in tortuous and small caliber vessels posing a high risk of thrombosis like visceral arteries, besides being costlier [ 36].
Distinguishing between adenocarcinomas of endocervical and endometrial origin histologically can be difficult, particularly in small biopsies.
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CEO of Professional Science Editing for Scientists @ prosciediting.com