Sentence examples for be difficult in randomized from inspiring English sources
So, it can be difficult in randomized clinical trials (RCT) to unambiguously attribute any clinical benefit to specific mechanisms.
Comparison with surgical data is difficult in the absence of randomized trials; the patients treated in the above trials were invariably medically inoperable, which has an impact on overall survival rates.
Difficult students are difficult in detention too.
That's difficult in academe".
The difference in patient-reported outcomes between study arms can often be difficult to ascertain in randomized controlled trials (RCTs) using a parallel design because of wide interindividual variations in baseline characteristics and how patients interpret the outcome measures.
This is difficult to achieve in randomized trials [ 19] other than pragmatic randomized trials [ 23].
This would be difficult to test in a randomized controlled trial, as postoperative mortality is very low after joint replacement (Parry et al. 2008, Cusick and Beverland 2009).
Given that pregnant women are subject to human-subject protection in clinical studies, it will be difficult to conduct a randomized trial.
But in defending her research, Dr. Mundinger pointed out that it would be difficult to conduct a careful, randomized study on the general population, because few people are willing to be randomly assigned to a doctor or nurse.
This is an important observation because many questions that could be addressed using similar analytic methods in large databases are difficult to address in randomized trials because of cost constraints or design complexity.
