Prediction of an individual's risk for cardiovascular disease is difficult, in particular in younger women due to low sensitive and specific tests for these women.
The stated problem is quite difficult, in particular for microarrays, since the inferred prediction must be sensible enough to capture the inherent biological structure in a dataset, e.g., functionally related genes.
The truth is, presents or no, business trips can be difficult for families, and for children in particular.
Most analysis programs for inferring molecular phylogenies are difficult to use, in particular for researchers with little programming experience.
In addition, it may be difficult for female officers in particular to find a partner if they join the service single.
And yet, for all of its appeal to the civic principles of inclusion, this liberal legacy was grounded in "Anglo-Saxon" culture, making it difficult in particular for Jews and Italians and especially for Asians and African Americans to gain acceptance.
Notwithstanding, the versatility and usefulness of integrated distributed hydrological models, parameterization requires substantial amounts of spatial data (Hallema et al., 2013), which can be difficult to obtain for soil hydraulic models in particular (Gumiere et al., 2015; Hallema et al., 2015a, b).
On the other hand, it would be difficult to account for these findings, and in particular the effects of the R444M mutation, with an external placement of the coiled coil (Lee et al., 2003, 2007).
Inspite of the wide spectrum of research activities and industrial developments in the mechatronic field it seems to be difficult for the design engineer in practice - in particular for the still unexperienced one - to select the suitable procedures, methods and tools for his design task.
There would be difficult issues for the Electoral Commission to resolve – in particular whether there should be just two alternatives or three.
