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While it may be difficult for scientists to get their hands on intact hyena brains, hyena skulls are not so hard to come by.
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Because silver's antibacterial attack is multi-pronged, the precise mechanism at work is difficult for scientists to pin down.
But because most of the plant materials that primates have been observed to dabble with are chemically complex, composed of hundreds if not thousands of compounds, it has been difficult for scientists to demonstrate that the animals were seeking a specific ingredient from any given sample.
It has been difficult for scientists to investigate changes in mood.
Traditionally, jumping from a long-term industry job back to academia or vice versa has been difficult for scientists, but that may be changing.
Still, it has been difficult for scientists to get a handle on how acidification and rising sea-surface temperatures affect reefs because growth can be so variable and hard to measure long-term.
It's difficult for scientists to directly connect powerful storms to rising global temperatures around the planet.
It is difficult for scientists to ascertain a precise number because many of the bodies have been lost or destroyed.
The cicadas' long subterranean youth, which may be the longest of any known insect, means it's difficult for scientists to study their life cycle.
Kipnis explained that the vessels are "well hidden" behind a major blood vessel to the sinuses in an area of the brain that's difficult for scientists to image.
But the DBP disease connection is difficult for scientists to fully evaluate because methods for measuring exposure have been imprecise.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com